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Colorado Activists File Ballot Initiatives To Legalize Psilocybin

Updated: Jun 16, 2022

The Colorado Psilocybin Mushroom Decriminalization and Therapy Program Initiative may appear on the ballot in Colorado as an initiated state statute on November 8, 2022.


The initiative would:

  • decriminalize the personal use of psilocybin mushrooms for adults age 21 and older;

  • create a natural medicine services program for the supervised administration of psilocybin mushrooms;

  • create a framework for regulating the growth, distribution, and sale of mushrooms to permitted entities; and

  • create the Natural Medicine Advisory Board to implement the regulated access program

Proponents filed two versions of the initiative. The provisions contained vary slightly in each version.


A growing body of medical research suggests that psilocybin and other psychedelic drugs could help treat anxiety, depression, post-traumatic stress disorder and addiction. That promise has given rise to dozens of companies eventually hoping to cash in.


A link to each initiative can be found here:





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